Thursday 13 August 2026 | The Daily Papule

No. 43 · 13 Aug 2026Thursday 13 August 2026: 50 papers from 18 journals← Wednesday’s edition Friday’s edition →

Efficacy and safety of upadacitinib in adults and adolescents for treatment of non-segmental vitiligo (Viti-Up)

results of two phase 3 randomised controlled studies.

ConclusionUpadacitinib 15 mg daily provides clinically meaningful repigmentation of both the face and total body for adults and adolescents with non-segmental vitiligo, with no new safety signals identified.

Passeron T, Prajapati VH, … senior author Seneschal JThe Lancet

Full abstract Read at publisher(opens in a new tab)

JAADObservational study
Relapse of alopecia areata during ongoing Janus kinase inhibitor therapy is not uncommon and usually occurs in previously affected areas
A multicenter Italian real-world study.
Sechi A, Rapparini L, … senior author Starace MJournal of the American Academy of Dermatology
JAADObservational study
Comparative outcomes of sebaceous carcinomas in Muir-Torre syndrome versus sporadic cases
A retrospective cohort study.
Erfani YJ, Ong MM, … senior author Rossi AJournal of the American Academy of Dermatology
Arch Derm ResObservational study
Opioid prescription patterns for hidradenitis suppurativa in the emergency versus ambulatory care settings
Kikuchi R, Tolson H, … senior author Armstrong AWArchives of Dermatological Research

Cutis
Medical Decision-Making in Evaluation and Management Coding
Practical Applications and Key Clarifications.
Elston DMCutis
PhotodermLaboratory research
Evaluating the Efficacy of Sunscreen Formulas in Reducing UV Filter Permeation Into the Stratum Corneum via In Vivo Confocal Raman Spectroscopy
Insights and Applications for Practical Suncare Product Design.
Zhang T, Lu H, … senior author Chen JPhotodermatology, Photoimmunology & Photomedicine
Clin Exp Derm
Old molecule, new scrutiny
Benzoyl peroxide in dermatology.
Lim AXH, Raza S, … senior author Ali FRClinical and Experimental Dermatology
IJD
Bereavement and Dermatologic Disease
An Underrecognized Clinical Consideration.
Hengy M, Hannawa O, … senior author Mehregan DInternational Journal of Dermatology
J Derm TreatObservational study
Clinical predictors of early treatment response across systemic therapies in psoriasis
a prospective cohort study.
Muheyati D, Jiang Y, … senior author Shi YJournal of Dermatological Treatment
Acta DVObservational study
Real-world Effectiveness and Safety of Lebrikizumab in Atopic Dermatitis: A TREATgermany Analysis.
Kind B, Pham C, … senior author Werfel TActa Dermato-Venereologica
J Dermatol
Treatment of Vulvar Lichen Sclerosus With Topical Ruxolitinib: A Single-Center Study.
Paganelli A, Colonna L, … senior author Picardo MJournal of Dermatology
Melanoma ResLaboratory research
Dissecting the interplay between dedicator of cytokinesis 2 and neutrophil extracellular traps in sculpting the immune landscape and clinical outcome of melanoma using a single-cell atlas.
Feng C, Yang X, … senior author Zhang YMelanoma Research
J Cosmet Derm
Evaluation of the Efficacy and Safety of Low-Energy Versus High-Energy Radiofrequency for the Treatment of Mild to Moderate Neck Wrinkles
A Split Neck Study
Tao J, Zhu Z, … senior author Liu ZJournal of Cosmetic Dermatology
J Cosmet DermLaboratory research
Evaluating Cosmetic Efficacy
A Comparative Study on Methods for Assessing Skin Redness Reduction and Soothing
Du Y, Li J, … senior author Wang FJournal of Cosmetic Dermatology
IJDObservational study
Prognostic Impact of Detection Patterns, Reasons for Consultation, and Sex Differences in Melanoma Among Young Adults
A 30-Year Retrospective Cohort Study.
Rodríguez-Sánchez B, Avilés-Izquierdo JA, … senior author de la Cueva-Dobao PInternational Journal of Dermatology
Acta DVObservational study
Machine-learning-based Phenomapping of Patients with Keratinocyte Carcinoma
Data-driven Subgrouping by Disease Burden, Comorbidities and Socioeconomic Status.
Sieborg J, Wenande E, … senior author Haedersdal MActa Dermato-Venereologica
CutisObservational study
Association Between Hidradenitis Suppurativa and Polycystic Ovary Syndrome.
Gill M, Babaei N, … senior author Wu JJCutis
J Cutan Pathol
AI Simplification of Dermatopathology Reports for Patients
Basic Versus Prompt-Engineered Approaches.
Nahm WJ, de Luzuriaga AMR, … senior author Nambudiri VEJournal of Cutaneous Pathology
Arch Derm ResObservational study
Mendelian randomization reveals causal links between celiac disease and inflammatory skin diseases
Qu P, Zhang K, Yang BArchives of Dermatological Research
Arch Derm ResObservational study
Clinical and immunological profiles of antinuclear antibody positivity in chronic spontaneous urticaria: a case-control study
Arslan A, Güçlü AOArchives of Dermatological Research
Arch Derm ResObservational study
A cross-sectional analysis of racial composition in dermatologic clinical trials completed in the United States from 2000 to 2023
Ituarte BE, Sullivan CM, … senior author Wei EXArchives of Dermatological Research
Arch Derm ResObservational study
Associations of xanthelasma palpebrarum and arcus senilis with cardiovascular disease: a trinetx analysis
Warne MM, Khan S, … senior author Wladis EJArchives of Dermatological Research
J DermatolReview
Systemic Treatment of Psoriasis
Current Evidence on Efficacy and Safety.
Hagino T, Kanda NJournal of Dermatology
JCMSReview
The Metabolic Revolution in Dermatology
Obesity, Insulin Resistance, and Ultra-Processed Diets as Drivers of Skin Inflammation.
Khalaf R, Chow W, … senior author Litvinov IVJournal of Cutaneous Medicine and Surgery
CutisReview
Getting a Grip on Occupational Hand Dermatitis
Key Considerations for Evaluation and Management.
Vu TN, Gui M, … senior author Reeder MCutis
Lancet
Oral JAK inhibitors for vitiligo
a new era of innovation.
Eleftheriadou VThe Lancet
JAAD
Clinical spectrum and emerging therapeutic approaches in trigeminal trophic syndrome
Diagnostic challenges and pitfalls.
Nukaly HY, Barker CS, Elston DMJournal of the American Academy of Dermatology
JAADLetter
Isotretinoin and Kashrut
Navigating gelatin capsules for observant Jewish patients.
Smith AD, Shulman MAJournal of the American Academy of Dermatology
JAADLetter
Hispanic ethnicity as an unconsidered variable in the obesity‑atopic dermatitis relationship.
Smith AD, Edmonds N, Carr CLJournal of the American Academy of Dermatology
JAADLetter
Ethical considerations for chronic topical therapy in safety-net clinics.
Moon J, Al-Dojaily Y, … senior author Grant-Kels JMJournal of the American Academy of Dermatology
JAADLetter
Accredited compounding pharmacies
A complementary approach to injectable triamcinolone acetonide shortages.
Smith AD, Schwartzman G, Hickman AWJournal of the American Academy of Dermatology
BJD
Clarifying denominators and statistical reporting in methotrexate maintenance for bullous pemphigoid.
Zhu XBritish Journal of Dermatology
BJD
Actinic Prurigo in Scotland - What Have we Learnt Over the Years?
Tan CH, Dawe RS, Ibbotson SHBritish Journal of Dermatology
JEADV
Hiding my hands
A patient perspective on nail lichen planus.
Golbasi NC, Lipner SRJournal of the European Academy of Dermatology and Venereology
JEADVLetter
Awareness of hidradenitis suppurativa and counselling practices among Danish pharmacy staff.
Ingadottir K, Andersen RK, … senior author Saunte DMLJournal of the European Academy of Dermatology and Venereology
CutisCase report
Using Intralesional Adalimumab for Chronic Refractory Cutaneous Granulomatous Inflammation.
Nukaly HY, Srikakolapu S, Elston DMCutis
Cutis
Multiple Grouped Erythematous to Violaceous Preauricular Papules.
Raman A, Gupte R, Mishra NCutis
IJDLetter
Erythroderma Following Initiation of Nemolizumab Therapy in Atopic Dermatitis.
Khalil N, Jackson-Cowan L, Yosipovitch GInternational Journal of Dermatology
J DermatolLetter
Alopecia Areata Associated With a Dominant AIRE Variant.
Yan Q, Zhang C, … senior author Li MJournal of Dermatology
Cutis
Consumer Trends Driving Contact Dermatitis
Insights from JiaDe Yu, MD, MS.
Yu J, Hoppel AM, Sonners ACutis
Cutis
Atopic Dermatitis
New Insights and Expanded Treatment Options.
Smith M, Usatine RP, Heath CRCutis
Cutis
Exophytic Papule on the Hand.
Afvari S, Patel AK, … senior author Pomeranz MKCutis
Clin Exp Derm
General Dermatology.
Lee ML, Affleck AClinical and Experimental Dermatology
Arch Derm Res
Hidradenitis suppurativa severity and anemia in an underinsured tertiary care population
Theriot T, Goldstein R, … senior author Haas CArchives of Dermatological Research
Cutis
Pink Papulonodular Eruption on the Trunk and Arms.
Lanehart MH, Dougher MC, … senior author Ghareeb ECutis
Arch Derm Res
Delafloxacin as a new therapeutic tool for the treatment of skin and soft tissue infections
experience in a single center
Sato VAH, de Menezes Neves PDM, … senior author Piastrelli FArchives of Dermatological Research
Acta DVCase report
Enalapril, Atenolol, Alendronate and DRESS Syndrome - A Case Report.
Olsson SB, Ehinger MActa Dermato-Venereologica

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