AJCDMeta-analysisSystematic review
Impact of Biologic Therapies on the Risk of Progression from Psoriasis to Psoriatic Arthritis
A Systematic Review and Meta-Analysis of Cohort Studies.
ConclusionBiologic therapy for psoriasis, particularly IL-23/IL-17-targeted agents, is associated with reduced incident psoriatic arthritis risk. These findings suggest early pathway suppression may delay clinical psoriatic arthritis diagnosis, though causal inference is limited by the observational data.
Xie W, Chen T, … senior author Xiao SAmerican Journal of Clinical Dermatology