Thursday 1 October 2026 | The Daily Papule

No. 92 · 1 Oct 2026Thursday 1 October 2026: 51 papers from 18 journals← Wednesday’s edition Friday’s edition →

Sonelokimab, a novel IL-17A- and IL-17F-inhibiting nanobody for the treatment of moderate-to-severe hidradenitis suppurativa

a global, randomized, double-blind, placebo-controlled phase 2 clinical trial (MIRA).

ConclusionSonelokimab demonstrated high levels of clinical response in patients with moderate-to-severe HS and was well tolerated.

Kimball AB, Bechara FG, … senior author Kirby BJournal of the American Academy of Dermatology

Full abstract Read at publisher(opens in a new tab)

Also in this edition

JAADMeta-analysisSystematic review
Treatment response and associated factors of hemoporfin-mediated photodynamic therapy for port-wine stains
a systematic review and meta-analysis.
Qi J, Wang Y, … senior author Jiang XJournal of the American Academy of Dermatology
BJDRCT
A UV-Free Strategy for Vitamin D Synthesis in Skin
Concept Verification and a Randomised Double-Blind Placebo-Controlled Clinical Trial of a Cholecalciferol Phosphate Patch (TransVitD).
Kawashita M, Lim CH, … senior author Jones SABritish Journal of Dermatology
Derm TherRCT
AI-Assisted Quantitative Reflectance Confocal Microscopy Reveals Modulation of Senescence-Associated Epidermal Morphometric Features by a Topical TGF-β Mimetic, XEP™-716 Miniprotein™.
Chajra H, Rayroux N, … senior author Le Doussal JMDermatology and Therapy

JAADClinical trial
Early use of mepolizumab in DRESS (Drug Reaction with Eosinophilia and Systemic Symptoms) syndrome
A prospective multicenter, open-label, pilot study.
Yun J, Richardson R, … senior author Carr AJournal of the American Academy of Dermatology
Derm TherClinical trialReview
Rezpegaldesleukin and Regulatory T Cell Restoration in Immune-Mediated Skin Diseases.
Domingues J, Chovatiya R, … senior author Torres TDermatology and Therapy
Derm TherClinical trial
Patterns of Clinical Response in Rollover Adolescent Patients with Alopecia Areata Treated with Ritlecitinib in the Ongoing Long-Term, Open-Label, Phase 3 ALLEGRO-LT Study.
Blume-Peytavi U, Craiglow B, … senior author Tran HDermatology and Therapy

Arch Derm ResSystematic review
Dermoscopic and reflectance confocal microscopic features of sebaceoma, sebaceous adenoma and sebaceous carcinoma: a systematic review
Scotti B, Baraldi C, … senior author Dika EArchives of Dermatological Research
Clin DermClinical trial
GLP-1 receptor agonists in psoriasis management.
Cutrona M, Talia J, Cices AClinics in Dermatology
J Cosmet DermClinical trial
Clinical Outcomes of Sequential Long-Pulsed 1060-nm and 805-nm Laser Treatment for Mid- and Lower-Face Aging
A Single-Arm Prospective Study
Wang L, Yuan X, … senior author Gao LJournal of Cosmetic Dermatology
ScienceLaboratory research
Loss of the tumor suppressor p53 generates a signaling gradient that drives epithelial clonal expansion.
Gan Q, Li W, … senior author Beronja SScience
JAADObservational study
Usefulness of neutrophil-to-lymphocyte ratio in the prognosis of cutaneous squamous cell carcinoma
a single-center retrospective cohort study.
Cardona-Machado C, Felices B, … senior author Cañueto JJournal of the American Academy of Dermatology
JAAD
Collaborative Multicenter Prognostication and Staging System for Cutaneous Squamous Cell Carcinoma (COMPASS-SCC).
Shahwan KT, Voller LM, … senior author Carr DRJournal of the American Academy of Dermatology
JAADObservational study
Finasteride tapering allows continuation of therapy in men with male pattern hair loss who develop sexual side effects: A retrospective study.
Kushnir-Grinbaum D, Dias FR, … senior author Bhoyrul BJournal of the American Academy of Dermatology
BJDLaboratory research
K17 hi Hair Follicle Cells Orchestrate Psoriatic Inflammation Through S100A1-Dependent Signaling.
Tang X, Qiao P, … senior author Shao SBritish Journal of Dermatology
JIDLaboratory research
TLR4 epidermal genetic deletion protects against acute and tumorigenic UV exposure in SKH-1 mouse skin.
Dickinson SE, Jandova J, … senior author Wondrak GTJournal of Investigative Dermatology
JIDLaboratory research
A Long-term Subcutaneous Flap-Protected Xenograft Model of Hidradenitis Suppurativa Preserves Active Tunnel Progression and Immune Microenvironment.
Delliturri M, Chiu E, Lu CPJournal of Investigative Dermatology
JEADV
Psychiatric morbidity, genetic susceptibility and the risk of vitiligo.
Yu Y, He M, … senior author Lu YJournal of the European Academy of Dermatology and Venereology
JEADV
IADVL consensus recommendations on Trichophyton indotineae infections
Using modified Delphi method.
Khurana A, Jayaraman J, … senior author Dogra SJournal of the European Academy of Dermatology and Venereology
JEADVLaboratory researchLetter
Clinical and transcriptomic evidence for systemic neutrophil activation in hidradenitis suppurativa.
Moon S, Na H, … senior author Shin JUJournal of the European Academy of Dermatology and Venereology
DermatitisObservational study
Age-Related Patterns in Anogenital Allergic Contact Dermatitis: A Retrospective Study.
Gilboa S, Koren O, … senior author Baum SDermatitis
DermatitisObservational study
North American Contact Dermatitis Group Patch Test Results: 2023-2024.
Reeder MJ, Broman AT, … senior author DeKoven JGDermatitis
Derm Surg
Fractional Lasers for Hair Restoration: A Scoping Review.
Sous D, Kamrani P, … senior author Fabi SDermatologic Surgery
J Cosmet DermObservational study
Knowledge, Attitudes, and Behaviors Regarding Laser Hair Removal of Medical Students: A Cross-Sectional Study
Atay E, Erdoğan HK, … senior author Metintaş SJournal of Cosmetic Dermatology
Derm Surg
Central Tumor Debulking in Mohs Micrographic Surgery
Technical Variations, Staging Utility, and Operational Efficiency.
Lewis DJDermatologic Surgery
Derm Ther
International Validation of the Short Version of the Quality of Life Relevance-Acne Questionnaire.
Chernyshov PV, Pustišek N, … senior author Dréno BDermatology and Therapy
J Cosmet Derm
A Sequential Treatment of Keloids
Multiple-Hole Punch Excision Combined With Superficial Radiation and Drug
Gong Z, Jing W, … senior author Tao XJournal of Cosmetic Dermatology
Derm TherObservational study
Long-Term Disease Control During Continuous Treatment with Upadacitinib and Baricitinib for Moderate-to-Severe Atopic Dermatitis
a Real-World Monocentric Retrospective Study.
D'Oria F, Falcidia C, … senior author Gargiulo LDermatology and Therapy
Derm TherObservational study
Window of Opportunity and Predictors of Sustained Remission in Patients with Hidradenitis Suppurativa Treated with Adalimumab
A 540-Patient Cohort Study.
Vilarrasa E, Garbayo-Salmons P, … senior author Romaní JDermatology and Therapy
Pediatr DermObservational study
Morphological Variations and Anatomical Distribution of Atypical Eschars in Pediatric Scrub Typhus
A Prospective Observational Study.
Narayanasamy DK, Arun Babu T, … senior author Mathiyalagen PPediatric Dermatology
Dermatitis
Allergens and Marketing Claims of Popular Over-the-Counter Deodorants.
Joshi A, Giuffre SN, … senior author Shi VYDermatitis
Derm Surg
Effectiveness and Safety of a High G' Hyaluronic Acid Injectable for Jawline Definition
A Randomized Controlled Clinical Investigation.
Shridharani SM, Ablon G, … senior author Bromée TDermatologic Surgery
Arch Derm ResObservational study
Enhancing quality of life through patient education and support in autoimmune blistering diseases
a prospective cohort study
Lillich ML, Myers EL, … senior author Culton DAArchives of Dermatological Research
JEADVReview
Systemic pruritus as a neuroimmune disorder
Mechanistic insights and target-driven therapy.
Reinhart S, Marijn S, … senior author Jo LJournal of the European Academy of Dermatology and Venereology
Derm TherReview
OX40 Ligand/OX40 Axis as the Inflammatory Prequel in Atopic Dermatitis: A Narrative Review.
Kwatra SG, Guttman-Yassky E, … senior author Chung CHDermatology and Therapy
Exp DermReview
The Spatiotemporal Coupling Imbalance of Senescent Grey Hair
Remodelling of the HFSC-MeSC-Niche Network and a New Paradigm of Stem Cell Senescence.
Xu H, Song XExperimental Dermatology
JAAD ReviewsReview
Measles Risk and MMR Vaccination Timing in Dermatology Patients on Immunosuppressive Therapy
Shen A, Hu AY, … senior author Tyring SKJAAD Reviews
JAAD
Improving Confidence With Vulvar-Directed Topical Therapy Through a Simplified Vulvar Anatomy Handout.
Silberzweig A, Frasier K, … senior author Shah PRJournal of the American Academy of Dermatology
JAAD
Bullous Pemphigoid.
Sagut P, Balan K, Elston DMJournal of the American Academy of Dermatology
JAAD
Clinical Characteristics and Survival Outcomes of Vulvar Leiomyosarcoma Compared with Cutaneous Leiomyosarcoma
A National Cancer Database Study.
Tran HTT, Le DV, … senior author Nguyen GHJournal of the American Academy of Dermatology
JAAD
Disease burden in rosacea by severity and clinical features - Findings from the Danish Skin Cohort.
Haugaard JH, Nymand L, Egeberg AJournal of the American Academy of Dermatology
BJD
MetaboHealth and Metabolic vulnerability index, genetic susceptibility, and the risk of psoriatic disease.
Shao X, Tan Z, … senior author Zhang JBritish Journal of Dermatology
BJD
Infection risk in psoriasis
not all biologics are the same.
Rivera-Diaz R, Pérez-Jacoiste Asín MBritish Journal of Dermatology
JEADVLetter
Myocardial dysfunction in psoriasis
Interpretation and clinical considerations.
Dons M, Skov L, Biering-Sørensen TJournal of the European Academy of Dermatology and Venereology
Am J DermpathCase report
Congenital Adnexal Carcinoma with Cribriform Pattern in a Pediatric Patient.
Koh E, Ajayi O, … senior author White KAmerican Journal of Dermatopathology
Clin Exp Derm
Patient-level adverse-event frequency may not reflect exposure-adjusted IVIG risk.
Kaplan FClinical and Experimental Dermatology
Derm Surg
Pyoderma Gangrenosum Arising in a Field of Superficial Radiation Therapy
A Novel Complication With Implications for Nonmelanoma Skin Cancer Management.
Nadir U, Jeha GM, Tolkachjov SNDermatologic Surgery
DermatitisCase report
A Case of Follicular Allergic Contact Dermatitis to Isopropyl Alcohol Swabs.
Yang VB, Crimp C, Vary JCDermatitis
Australas J DermCase report
The Role of NUDT15 in Azathioprine Toxicity
A Case of Recalcitrant Pityriasis Lichenoides Chronica.
Akdemir A, Zhang L, Wells JAustralasian Journal of Dermatology
J DermatolLetter
A Novel Heterozygous ALX4 Frameshift Variant Causing Congenital Diffuse Hypotrichosis and Frontonasal Dysmorphism.
Zhang F, Li F, … senior author Wang SJournal of Dermatology
Clin Exp Derm
A pruritic genital eruption in a young man with Crohn disease.
Iinuma S, Yamauchi H, Fujita YClinical and Experimental Dermatology

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