BJDRCT
Upadacitinib for Palmoplantar Pustulosis
An Open-label, Assessor-blinded Feasibility Study Using Historic Control Data (JAKPPPOT).
ConclusionThis study demonstrates that a definitive trial of JAK inhibition in PPP is feasible and identifies an encouraging exploratory efficacy signal. The findings support progression to a multicentre active-comparator randomised controlled trial.
Gleeson D, Chapman S, … senior author Smith CBritish Journal of Dermatology