Monday 6 July 2026 | The Daily Papule

Acta DVSystematic review

A Systematic Literature Review on Methotrexate Hepatotoxicity in Psoriasis Management

Preconceived Notion or Real Threat?

From the abstractWhile folic acid supplementation may mitigate risk, dosing remains inconsistent.Though MTX carries a potential hepatotoxic risk, this is patient-specific rather than inherent to the drug. Standardized monitoring protocols and risk stratification are essential to optimize safety, prevent unnecessary treatment discontinuation and improve long-term psoriasis management.

Boehncke WH, Constantin MM, … senior author Viguier MActa Dermato-Venereologica

Full abstract Read at publisher(opens in a new tab)

J Cutan PatholObservational study
Elevated IL-4 and IL-13 Expression in Hailey-Hailey Disease
Evidence for Th2-Mediated Pathogenesis and Targeted Treatment.
Gaumond SI, Soto V, … senior author Romanelli PJournal of Cutaneous Pathology
J Cosmet Derm
Efficacy and Tolerability of a Multi-Targeted Anti-Acne Regimen Incorporating Salicylic Acid, Prebiotics, and Zinc PCA
A 30-Day Clinical Trial
Armanious YM, Neaz OS, … senior author Abdelrahim NAJournal of Cosmetic Dermatology
Acta DVObservational study
Psychiatric Risk in Chronic Spontaneous Urticaria
A Retrospective Cohort Study.
Curman P, Olbrich H, … senior author Ludwig RJActa Dermato-Venereologica

Exp DermLaboratory research
Comparative Transcriptomics Reveals SKH-1 Mice as a Valuable Model for Psoriasis Pathogenesis and Recurrence Studies.
Yue L, Bai Y, … senior author Dang EExperimental Dermatology
Acta DV
Standardizing Prurigo Control Assessment Globally
Linguistic Validation and Cross-cultural Adaptation of Prurigo Control Test in 18 Languages.
Metz M, Weller K, … senior author Wiggins SActa Dermato-Venereologica
Acta DVObservational study
Dupilumab in Difficult-to-treat Chronic Spontaneous Urticaria
A Real-world Multicentre Cohort Study.
Planella-Fontanillas N, Berna-Rico E, … senior author Giménez-Arnau AMActa Dermato-Venereologica
Exp DermLaboratory research
SLURP2 Enlarges Adipocytes and Induces IL-23-Producing Macrophages in Murine Dermal Adipose Tissue.
Tsuji H, Mabuchi TExperimental Dermatology
JAADReview
Atypical fibroxanthoma, pleomorphic dermal sarcoma, and undifferentiated sarcoma
Updates on diagnosis, management, and surveillance.
Park JS, Erem AS, … senior author Samie FHJournal of the American Academy of Dermatology
JEADVReview
Cutaneous embryology
Physiological basis and clinical implications.
Martins F, Calvão J, … senior author Ramos LJournal of the European Academy of Dermatology and Venereology
BJD
Quality-of-life measurement in migrants and other vulnerable groups
experience with Skindex-16 in Malta and Lebanon.
Elyas A, Mohareb AM, … senior author Padovese VBritish Journal of Dermatology
BJD
Shallow cuts, deeper issues
the primacy of deep margins in cutaneous squamous cell carcinoma.
Misky AT, Paiva M, … senior author Pollock JBritish Journal of Dermatology
Derm Surg
Punch Debridement as an Alternative Minimally Invasive Technique in the Management of Hidradenitis Suppurativa: A Single-center Study.
Edek YC, Şahin S, … senior author Adışen EDermatologic Surgery
J Cosmet Derm
Factors Affecting the Efficacy of Monopolar Radiofrequency in Facial Rejuvenation
Zhao S, Yan YJournal of Cosmetic Dermatology
Pediatr Derm
Perianal Erosive Plaque: Diagnostic Challenge.
Guiot N, Aman A, … senior author Jackson SPediatric Dermatology
Acta DVCase report
Application of IL-17A Inhibitors in Psoriasis Complicated by Multiple Infections - Successful Treatment and Insights from a Case of Psoriasis with HIV and Neurosyphilis.
Mao TT, Yu FF, … senior author Qi MLActa Dermato-Venereologica
Acta DVQuiz & image
Erythematous Nodules and Plaques on the Neck: A Quiz.
Xiang Y, Mou Y, … senior author Chen RActa Dermato-Venereologica
Derm Surg
Evaluation of Lentigo Maligna With Additional Immunohistochemical Staining on Frozen Sections With PRAME, Melan-A, and SOX10.
Zoutendijk J, van den Bos RR, Mooyaart ADermatologic Surgery
Clin Exp Derm
Guselkumab for checkpoint inhibitor-exacerbated psoriasis in a patient with metastatic melanoma.
Conlon O, Herlihy M, … senior author O'Kane MClinical and Experimental Dermatology

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