Wednesday 9 September 2026 | The Daily Papule

No. 70 · 9 Sep 2026Wednesday 9 September 2026: 71 papers from 20 journals← Tuesday’s edition Thursday’s edition →

Drug Survival of Omalizumab and Factors Associated With Discontinuation in Chronic Urticaria: A Meta-Analysis.

ConclusionThe results of this systematic review and meta-analysis suggest that omalizumab demonstrates long-term drug survival in CU, with discontinuation more often due to disease control than adverse events. Autoimmune comorbidities (mainly thyroid-related) were associated with reduced drug survival, primarily due to lack of efficacy, whereas atopic comorbidities were associated with discontinuation after disease control, underscoring the need for improved endotype-driven treatment strategies.

Altayf A, Kolkhir P, … senior author Elhadi MJAMA Dermatology

Full abstract Read at publisher(opens in a new tab)

J Cosmet DermSystematic review
Stem Cell-Based Therapies for Skin Rejuvenation
A Systematic Review of Clinical Efficacy, Safety, and Underlying Mechanisms
Al-Dhubaibi MS, Mohammed GF, … senior author Aziz SSJournal of Cosmetic Dermatology
JCMSSystematic reviewLetter
Efficacy and Safety of Treatments for Alopecia Areata-Associated Nail Involvement: A Systematic Review.
Lordfard S, McMullen E, … senior author Sibbald CJournal of Cutaneous Medicine and Surgery
Derm SurgSystematic review
A Systematic Review of Patient-Reported Outcome Measures in Rare Skin Cancers: An Unmet Need.
Spoer DL, Caravan S, … senior author Kibbi NDermatologic Surgery

JCMSSystematic reviewLetter
Dupilumab in Kimura's Disease and Angiolymphoid Hyperplasia With Eosinophilia: A Systematic Review.
Varambally M, Shaker M, … senior author Liu CJournal of Cutaneous Medicine and Surgery
JCMSSystematic reviewLetter
Efficacy and Safety of Systemic Therapies for Darier Disease: A Systematic Review.
Bai JQA, Abubaker F, … senior author Mufti AJournal of Cutaneous Medicine and Surgery
JCMSSystematic reviewLetter
Off-Label Rituximab in Pediatric Autoimmune Blistering Diseases: A Systematic Review.
Abdul Ghafoor AA, Wen S, … senior author Khosravi-Hafshejani TJournal of Cutaneous Medicine and Surgery
JAADObservational study
Oral Janus kinase inhibitor-based combination therapy in pediatric vitiligo
A real-world retrospective cohort study.
Wang Z, Yue Z, … senior author Zhang FJournal of the American Academy of Dermatology
JAADObservational study
Prior keratinocyte carcinoma as a risk factor for mucosal melanoma
A multi-institutional retrospective case-control study of Veterans and civilians in the Veterans Health Administration and Mass General Brigham.
Huhmann LB, Hwang JC, … senior author Hartman RIJournal of the American Academy of Dermatology
JIDObservational studyLaboratory research
Blood proteomics links systemic inflammation with early atherosclerosis in moderate-to-severe atopic dermatitis.
Berna-Rico E, Neria F, … senior author González-Cantero ÁJournal of Investigative Dermatology
JIDLaboratory research
Time-course blood transcriptome dynamics of TNF-α inhibitor therapy in a Chinese cohort with psoriasis.
Xia Z, Liu L, … senior author Ren YJournal of Investigative Dermatology
JIDLaboratory research
Aging-related IgG accumulation promotes skin inflammation.
Suzuki T, Horiguchi H, … senior author Oike YJournal of Investigative Dermatology
JIDLaboratory research
A Bisubstrate Inhibitor of NNMT Suppresses Myofibroblast Reprogramming to Mitigate Skin Fibrosis.
Saba K, Kataria S, … senior author Varga JJournal of Investigative Dermatology
JIDObservational study
Distinct heart rate variability signatures characterize uremic pruritus in adults and children.
Du P, Ji L, … senior author Li FJournal of Investigative Dermatology
JIDLaboratory research
Defensins mediate skin inflammation and itch in psoriasis.
Balaji SK, Zheng Q, … senior author Dong XJournal of Investigative Dermatology
JIDLaboratory research
Postzygotic NRAS variants and subsequent copy-neutral loss of heterozygosity underlie speckled-pattern formation in nevus spilus-type congenital melanocytic nevus.
Ueda K, Yoshioka A, … senior author Kubo AJournal of Investigative Dermatology
JIDLaboratory research
Divergent cytotoxic and immunomodulatory immune programs distinguish morbilliform drug eruption from SDRIFE.
Chopp LB, Xing X, … senior author Gudjonsson JEJournal of Investigative Dermatology
JID
Veterans' willingness to use home-based telehealth and artificial intelligence for dermatology.
Peracca SB, Zepeda ED, … senior author Oh DHJournal of Investigative Dermatology
JIDLaboratory research
Fluoxetine activates melanocyte stem cells indirectly through the epithelial 5-hydroxytryptamine (5-HT) receptor 1A/Wnt signaling to regenerate melanocytes.
Zhang X, Song X, … senior author Shang JJournal of Investigative Dermatology
JIDLaboratory research
Tfh cell communication with myeloid compartments plays a key role in the inflammatory response in localized scleroderma
insights from skin scRNA sequencing.
Mirizio E, Werner G, … senior author Torok KSJournal of Investigative Dermatology
JIDLaboratory research
Disease progression-dependent neurobehavioral phenotypes of agitation, anxiety, and depression in MC903-induced chronic itch.
Chang H, Su M, … senior author Jiang RJournal of Investigative Dermatology
JIDLaboratory research
A proinflammatory FOLR2-positive macrophage subtype promotes cutaneous and renal damage in systemic lupus erythematosus.
Wen J, Chen W, … senior author Tao JJournal of Investigative Dermatology
Acta DV
Narrow-band UV-B (TL-01) Phototherapy Exposure and Skin Cancer Risk
A Nested Case-control Study.
Åkerla P, Pukkala E, … senior author Karppinen TActa Dermato-Venereologica
Exp Derm
AI-Based Segmentation of Wound Types Caused by Epidermolysis Bullosa.
Wimmer G, Puttinger C, … senior author Uhl AExperimental Dermatology
Acta DVLaboratory research
Connecting Skin and Gut in Dermatitis Herpetiformis
Insights from Gluten Challenge Transcriptomics.
Kaunisto H, Kemppainen E, … senior author Lindfors KActa Dermato-Venereologica
J Derm Sci
Postzygotic biallelic inactivation of FDFT1 underlies solitary lesion formation in porokeratosis of Mibelli.
Hashimoto S, Saito S, … senior author Kubo AJournal of Dermatological Science
Lasers Surg MedObservational study
Efficacy and Safety of Small-Spot 755 nm Picosecond Laser-Induced Optical Breakdown for Novel Photomechanical Skin Ablation in Asian Patients.
Chai NW, Liao WC, … senior author Chen YTLasers in Surgery and Medicine
Exp Derm
Future Integration of Biomarkers for Inflammatory Skin Diseases Into Daily Practice
A Survey Among a Multifaceted Group of Patients and Dermatological Care Providers.
Godding LTH, de Jong EMGJ, … senior author Seyger MMBExperimental Dermatology
Clin Derm
The menopause supplement gold rush
Ethical obligations in dermatology.
Chung J, Lipner SRClinics in Dermatology
Derm SurgObservational study
A Practical, Targeted Approach to the Treatment of the Platysma Muscle With Neuromodulator.
Rosen N, Muhn ODermatologic Surgery
Exp DermLaboratory research
Nicastrin Regulates Cutaneous Squamous Cell Carcinoma Progression Through the MAPK/ERK Signalling.
Xue S, Shen Y, … senior author He YExperimental Dermatology
Pediatr DermObservational study
Associations of Active and Passive Smoke Exposure and Hidradenitis Suppurativa in the Pediatric Population: A Case-Control Study.
Ziebart RL, Numani A, … senior author Mohandesi NAPediatric Dermatology
Arch Derm ResObservational study
The relationship between cutaneous viral warts and ABO/RH blood groups
a retrospective case-control study
Kanat Z, Türkmen D, … senior author Güner MEArchives of Dermatological Research
Derm SurgObservational study
Surgical Management and Outcomes of Atypical Fibroxanthoma and Pleomorphic Dermal Sarcoma: A Retrospective Cohort.
Currier J, Daines B, … senior author Murakawa GJDermatologic Surgery
Arch Derm ResObservational study
PHQ-9 depression screening in alopecia
a single-center cross-sectional study
Venkatesh T, Bosch L, … senior author Colavincenzo MLArchives of Dermatological Research
JEADVReview
Management of chronic urticaria
Current status and future prospect.
Salman A, Al-Ahmad M, … senior author Kocaturk EJournal of the European Academy of Dermatology and Venereology
IJDReview
Food Allergy Testing in Atopic Dermatitis
A Purpose-First Comparison of International Guidelines.
Chen WG, Chen CC, … senior author Ho WTInternational Journal of Dermatology
NEJMCase report
Case 25-2026
A 65-Year-Old Man with Fever and Rash.
Chu JT, Rasmussen RG, … senior author Su MYThe New England Journal of Medicine
JAMA Derm
US Food and Drug Administration's Adverse Event Reporting System-Highly Limited for Causal Inference in Dermatology.
Lu C, Margolis DJ, Beiter KJJAMA Dermatology
JAMA Derm
Diffuse Melanosis Cutis and Melanuria in Advanced Melanoma.
Breitenhuber N, Rohrer P, Kränke TJAMA Dermatology
JAMA Derm
Budget Impact Analysis of Gene Therapies for Recessive Dystrophic Epidermolysis Bullosa.
Raymakers AJN, Kesselheim AS, Feldman WBJAMA Dermatology
JAAD
Refining the Definition of Acral Melanoma
Histologic and Anatomic Considerations.
Beagles E, Khattab S, … senior author Semenov YRJournal of the American Academy of Dermatology
BJD
Health Domains and Outcome Measurement Instruments in Adult Vulvovaginal Lichen Planus Studies: A Scoping Review.
Roland-McGowan J, Simpson EL, … senior author Foster ELBritish Journal of Dermatology
BJD
Why do Australian dermatologists screen for Strongyloides stercoralis before dupilumab?
Lee T, Muhi S, Ross GBritish Journal of Dermatology
BJD
Beyond Publications
Why Dermatology Needs Research-on-Research (Meta-research).
Tan E, Williams HCBritish Journal of Dermatology
JID
Real-Life Performance of the Dermatology Long-Term Life Impact Measure (DLLIM) in Atopic Dermatitis
An International Study of 15,450 Patients.
Aslanian FP, Halioua B, … senior author Silverberg JIJournal of Investigative Dermatology
JEADVLetter
Major adverse cardiovascular events in atopic dermatitis treated with Janus kinase inhibitors.
Neildez M, Gundelwein M, … senior author Droitcourt CJournal of the European Academy of Dermatology and Venereology
JEADVLetter
Ropeginterferon alfa-2b in mycosis fungoides: A multicentre cohort.
Nikolaou V, Koumprentziotis IA, … senior author Siakantaris MJournal of the European Academy of Dermatology and Venereology
JEADVLetter
Efficacy evaluation of flap repair after radical excision for axillary hidradenitis suppurativa.
Yang Z, Peng S, … senior author Yang LJournal of the European Academy of Dermatology and Venereology
Am J DermpathCase report
Recurrent Primary Cutaneous Anaplastic Large Cell Lymphoma With T-Cell Receptor-ϒδ Phenotype and DUSP22-IRF4 Unbalanced Rearrangement
A Rare and Diagnostically Challenging Presentation.
Ibrahim E, Cho WC, … senior author Curry JLAmerican Journal of Dermatopathology
IJDLetter
Dynamic Nail-Bed Phenotyping in Onycholysis
Diagnostic Accuracy Remains Untested.
Gallo G, Quaglino P, Ribero SInternational Journal of Dermatology
JCMS
Lupus-Like Chilblains in a Patient With Myelodysplastic Syndrome.
Rivard LA, Lachance MJournal of Cutaneous Medicine and Surgery
Arch Derm Res
Isotretinoin suppresses key pro-inflammatory cytokines at transcriptional and systemic levels in acne vulgaris
Akan G, Bostanci A, … senior author Atalar FArchives of Dermatological Research
Arch Derm Res
Association of seborrheic dermatitis and psoriasis and impact on healthcare utilization in the United States
Pandey A, Hopkins T, … senior author Chovatiya RArchives of Dermatological Research
IJDLetter
Upadacitinib for Refractory Chronic Perianal Pruritus.
Aral HNE, Temirkaynak MK, … senior author Adışen EInternational Journal of Dermatology
JCMS
Linear Focal Elastolysis (Elastotic Striae).
Tyagi SJournal of Cutaneous Medicine and Surgery
Derm Surg
Reconstruction of a Complex Oral Commissure Defect After Mohs Surgery.
Rodríguez-Jiménez P, Vicente JDermatologic Surgery
Arch Derm Res
The potential of colorimetry in developing a clinical scale for post-inflammatory hyperpigmentation
Verma KK, Goldstein DR, … senior author Tarbox MBArchives of Dermatological Research
Arch Derm Res
Pre-surgical mapping of recurrent lentigo maligna of the face with handled confocal microscopy
a useful tool to downstage surgical repair
Venturi F, Veronesi G, … senior author Dika EArchives of Dermatological Research
Arch Derm Res
Incidence of isotretinoin-associated arthritis following isotretinoin initiation in pediatric patients: a scoping review
Rankin E, Juriga J, … senior author Riskin SIArchives of Dermatological Research
Derm Surg
Reduced Risk in Melanoma and Nonmelanoma Skin Cancers in Obese Patients on Semaglutide and Tirzepatide.
Alameddine R, Roecker A, … senior author Wagner RFDermatologic Surgery
Arch Derm Res
Differences in online patient reviews based on dermatologic surgeons’ gender
Maas D, Spindler A, … senior author Criscito MCArchives of Dermatological Research
Arch Derm Res
Optimizing keloid treatment
dermoscopy’s predictive power in corticosteroid response
Mu Y, Wang Y, … senior author Tian YArchives of Dermatological Research
IJDLetter
People of Color With Dermatofibrosarcoma Protuberans Experience High Rates of Fibrosarcomatous Change but No Local Recurrences After Mohs Micrographic Surgery.
Raj LK, Shaikh UR, … senior author Higgins HWInternational Journal of Dermatology
Dermatitis
Tea Time
Allergic Contact Cheilitis to Black Tea and Flavor Additives.
Alley DR, Abi H, Ophaug SDermatitis
IJDLetter
Infantile Bullous Pemphigoid and Linear IgA Bullous Disease Presenting as Hand-Foot-and-Mouth Disease With Positive Enterovirus PCR.
Chin NE, Poupart S, … senior author Vivar KLInternational Journal of Dermatology
JCMS
Dermoscopy of Cutaneous Sarcoidosis.
Faik Ouahab M, Kelati AJournal of Cutaneous Medicine and Surgery
Clin Exp Derm
Longitudinal variation in Phototherapy Cabinets - are extended height cabinets worth the additional expense?
Britton J, Montgomery R, Goulden VClinical and Experimental Dermatology

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