Isomorphic Response Following Laser Tattoo Removal.
Solomon M, Franklin JM, Roberts J, Hivnor C
Lasers in Surgery and MedicineIn the feed 26 Aug 2026, published online 26 Aug 2026, issue 2026 Aug 26, added to PubMed 26 Aug 2026
Topics: PsoriasisCosmetic, lasers, scars & wounds
Abstract
OBJECTIVESWe present a case of Koebnerized psoriasis following laser tattoo removal, a scenario that has not yet been reported in the current literature.
METHODSA 39-year-old male with plaque psoriasis was treated for tattoo removal with picosecond and CO2 laser therapies. He had two sessions of combined picosecond and CO2 treatments and one session of picosecond alone.
RESULTSOne month after the third session, he developed psoriasiform changes at the treated sites, consistent with an isomorphic response, and this was confirmed on histopathological examination.
CONCLUSIONSThis case is significant as Koebnerization after laser tattoo removal is not reported in the literature. It raises important considerations regarding the role of laser-induced dermal inflammation and the impact of tattoo pigments on psoriatic responses. The findings highlight the potential for laser therapies to exacerbate preexisting conditions like psoriasis, emphasizing the need for careful patient evaluation prior to treatment.
Abstract from PubMed
PMID 42646643 · DOI 10.1002/lsm.70199