The Daily Papule

Derm SurgRCT

Multimodal Facial Rejuvenation Using Integrated Radiofrequency, Microneedle Radiofrequency, and Dynamic Muscle Stimulation

A Prospective Randomized Controlled Trial.

Yu C, Wang Y, Kang H, Yao T, Zhang R, Liu X, Gao N, Yuan X, Gao L, Wang G

Dermatologic SurgeryIn the feed 21 Sep 2026, published online 22 Sep 2026, issue 2026 Sep 22, added to PubMed 21 Sep 2026

Topics: Cosmetic, lasers, scars & wounds

Abstract

BACKGROUNDFacial aging is a multilayered process involving the skin, subcutaneous tissue, and facial musculature.

OBJECTIVETo evaluate the efficacy and safety of an integrated radiofrequency (RF), microneedle radiofrequency (MNRF), and dynamic muscle stimulation (DMSt) approach for facial rejuvenation.

MATERIALS AND METHODSParticipants with moderate-to-severe facial wrinkles received 3 treatment sessions at 1-month intervals using a combined radiofrequency (RF), microneedle radiofrequency (MNRF), and dynamic muscle stimulation (DMSt) device, with clinical outcomes and safety evaluated during follow-up.

RESULTSSignificant improvement in facial wrinkles and overall appearance was observed at 1, 3, and 6 months after 3 treatments. All treated participants demonstrated improvement on the Global Aesthetic Improvement Scale (GAIS), whereas no improvement was observed in untreated controls (p < .001). Fitzpatrick-Goldman Wrinkle and Elastosis Scale (FWES) scores and patient satisfaction also improved. Although partial attenuation of effects was noted at later follow-up, outcomes remained superior to controls. Adverse events were mild, transient, and well tolerated.

CONCLUSIONThe combined RF, MNRF, and DMSt approach achieves significant, albeit partial, improvement with a favorable safety profile by targeting both skin and underlying musculature.

Abstract from PubMed

PMID 42766316 · DOI 10.1097/DSS.0000000000005349