The Daily Papule

J Cosmet Derm

Beyond Volumization

Repositioning Hyaluronic Acid Fillers as Anatomy-Guided Structural Support Tools in the Era of Biostimulators

Margarella T, Shin SJ

Journal of Cosmetic DermatologyIn the feed 2 Sep 2026, published online 1 Sep 2026, issue 2026 Sep

Topics: Cosmetic, lasers, scars & wounds

Abstract

BACKGROUNDHyaluronic acid (HA) fillers remain widely used in facial rejuvenation, yet concern about overfilled syndrome and unnatural volumization has shifted attention toward biostimulators. These concerns may reflect a mismatch between volumetric treatment logic and structural problems of facial aging.

OBJECTIVETo propose an anatomy-guided framework that repositions HA fillers from default volume replacement toward selective structural support and lifting-oriented treatment planning.

METHODSA targeted narrative review of anatomical, clinical, rheological, biological, and vascular-safety literature was conducted using PubMed, Google Scholar, and relevant journal databases through July 2026.

RESULTSFacial aging involves skeletal remodeling, fat-compartment changes, dermal deterioration, and altered relationships among retaining ligaments and mobile soft tissues. Ligament-associated HA injection is best interpreted as mechanical scaffold augmentation in selected periosteal or periligamentous support zones rather than injection into the ligament itself or ligament regeneration. Current evidence supports the plausibility of support-mediated contour improvement but does not establish true tissue repositioning independent of projection or volumizing effects. Product selection should consider plane, function, G′, cohesivity, viscosity, swelling tendency, and vascular risk rather than G′ alone. HA and biostimulators have complementary and overlapping roles.

CONCLUSIONHA fillers should not be viewed as obsolete because of overfilling. Appropriate patient selection, anatomy-guided planning, conservative dosing, region-specific product selection, and vascular safety may allow HA to function as a structural support tool. The future of HA filler treatment is not less HA, but better-directed HA.

Abstract from Crossref

DOI 10.1111/jocd.71179 · Not in PubMed: details from Crossref