Cardiac Sarcoidosis in Patients With Cutaneous Sarcoidosis

Sarcoidosis affects various organs, with cardiac involvement being clinically crucial due to its impact on prognosis. To date, there have been few reports on the association between cutaneous manifestations and cardiac sarcoidosis. We retrospectively examined 111 patients with cutaneous sarcoidosis and identified cardiac sarcoidosis in 16 patients (14.4%, 4 males and 12 females). The skin lesions were plaque (n = 7), nodular (n = 4), subcutaneous (n = 3), scar (n = 3), and lupus pernio (n = 1) types. A statistically significant correlation was observed between facial plaque-type cutaneous sarcoidosis and cardiac sarcoidosis. Although the examined number is small, our results suggest that plaque-type sarcoidosis in the face may be a useful sign for considering cardiac involvement. Further studies are necessary to elucidate the association of cutaneous and cardiac sarcoidosis.

Abstract from PubMed