Effects of High-Dose Multichannel Radiofrequency Treatment on Visceral and Subcutaneous Abdominal Fat

OBJECTIVESEnergy-based devices (EBDs) have been used as a radiofrequency treatment for abdominal obesity, although their effects on visceral fat are not well known. This study aimed to evaluate the impact of applying an EBD treatment on visceral and subcutaneous adipose tissue, anthropometric values, lipid profile, adipokines, and the insulin resistance index.

METHODSWe conducted a prospective pre–post interventional study in a single outpatient clinical body-contouring facility in Barcelona, Spain. Twenty adults (10 men, 10 women; mean age 49 ± 11 years) with BMI 25–< 30 kg/m2, abdominal obesity, and visceral fat score > 9 were treated with EBD-radiofrequency using the Endoxslim device: 10 sessions of 60 min plus 20 min with capacitive and resistive electrodes at temperature > 45°C. We analyzed anthropometric changes, and visceral and subcutaneous fat were quantified by magnetic resonance imaging. Serum samples were obtained at the beginning and end of treatment for the quantification of the biochemical variables.

RESULTSAt the end of the treatment period, patients significantly reduced waist circumference, systolic blood pressure levels, and visceral and subcutaneous fat mass (p < 0.05). In addition, leptin levels, basal insulinemia, and HOMA-IR index were also reduced (p < 0.05). No adverse effects were reported.

CONCLUSIONSEBD is a safe and effective method to reduce subcutaneous and visceral fat in abdominal obesity, with consequent improvement in the metabolic profile. ClinicalTrials.gov Identifier: NCT06377358.

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