A Technique for the Generation of Mucosal and Acral Melanoma Cell Lines.
Banik I, Basu S, Wang M, Escobar AJ, Steri V, Camara Serrano JA, Phojanakong P, Pacheco NC, Tsai KK, Alvarez EA, Daud A, El-Sayed IH, Samarkina A, Xu J, Aquino JD, Xiao M, Herlyn M, Yeh I
Pigment Cell & Melanoma ResearchIn the feed 5 Sep 2026, issue 2026 Sep, added to PubMed 5 Sep 2026
Topics: Skin cancer & tumors
Abstract
Mucosal and acral melanomas are rare subtypes of melanoma with unique clinical and biological features. A dearth of well-established and characterized melanoma cell lines that reflect rare subtypes impedes research on these lethal diseases. We present a protocol developed by exploring various combinations of established techniques that we used to generate mucosal and acral cell lines from patient tissues and patient derived xenografts.
Abstract from PubMed
PMID 42698217 · DOI 10.1111/pcmr.70117