The Daily Papule

Am J Dermpath

A Look Back at Mercury Soap as a Treatment for Yaws.

Papalas JA

American Journal of DermatopathologyIn the feed 18 Sep 2026, published online 16 Jul 2026, issue 2026 Oct 01, added to PubMed 18 Sep 2026

Topics: Infections & infestationsDermatopathology

Abstract

The centuries-old practice of using mercury as a treatment for syphilis is well-known. The historical use of mercury for other treponematoses is less well-recognized. Afridol was a mercury containing soap produced by Bayer which they promoted as a cure for various cutaneous aliments, including yaws (frambosia). In this article, I briefly outline the development of Afridol and its subsequent marketing with the use of early 20th century medical advertising art.

Abstract from PubMed

PMID 42758882 · DOI 10.1097/DAD.0000000000003364